| Number of Government-Funded Projects Undertaken | 13 projects | All successfully completed between 2016 and 2024 |
|---|
| Number of Publications | 10 papers |
Related to ATB1651 : 3 papers
Related to Drug Targets : 3 papers
|
|---|---|---|
| Key Publications |
Journal of Medicinal
Chemistry
(IF : 8.039) 
Nature
Communications
(IF : 17.694) 
|
|
| No. | Description | Pipeline | Status | Remark |
|---|---|---|---|---|
| 1 | 감염성 진균의 바이오필름 생성을 억제하는 신규한 항진균용 조성물 | ATB1651 | PCT 출원 | 미국 유럽 중국 일본 등 13개국 출원? |
| 2 | 신규한 아미노알칸산에 바이페닐기를 도입한 유도체 화합물 및 이를 포함하는 항진균성 약학적 조성물 |
ATB1651 | PCT 출원 한국 등록 |
| Date of publication | The title of paper | Academic journal |
|---|---|---|
| 2024.02 | Toxicity of a novel antifungal agent (ATB1651 gel) in Yucatan minipigs (Sus scrofa) following 4 weeks of daily dermal administration | Toxicological Research |
| 2024.01 | Casein kinase 2 complex: a central regulator of multiple pathobiological signaling pathways in Cryptococcus neoformans | mBio |
| 2023.04 | Adenylyl-Sulfate Kinase (Met14)-Dependent Cysteine and Methionine Biosynthesis Pathways Contribute Distinctively to Pathobiological Processes in Cryptococcus neoformans | Microbiology Spectrum |
| 2022.03 | The novel antifungal agent AB-22 displays in vitro activity against hyphal growth and biofilm formation in Candida albicans and potency for treating systemic candidiasis | Journal of Microbiology |
| 2021.11 | Optimization and evaluation of novel antifungal agents for the treatment of fungal infection | Journal of Medicinal Chemistry |
| 2020.03 | Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans | Nature Communications |
| 2019.11 | In Situ Self-Cross-Linkable, Long-Term Stable Hyaluronic Acid Filler by Gallol Autoxidation for Tissue Augmentation and Wrinkle Correction | Chemistry of Materials |
| 2018.02 | Ascidian-Inspired Fast-Forming Hydrogel System for Versatile Biomedical Applications | Advanced Functional Materials |
| 2016.09 | Systematic Functional analysis of kinases in the fungal pathogen Cryptococcus neoformans | Nature Communications |
| 2015.04 | Systematic Functional Profiling of Transcription Factor Networks in Cryptococcus neoformans | Nature Communications |
| No. | Institution | Project | Date | Status |
|---|---|---|---|---|
| 1 | 보건복지부 | 보건의료기술연구개발 사업 (ATB1606) | 2023.07. ~ 2025.12. | In progress |
| 2 | 범부처 | 국가신약개발사업 (R&D) (ATB1606) | 2023.06. ~ 2025.05. | In progress |
| 3 | 보건복지부 | 감염병 예방치료 기술개발 (다제내성 그람음성균 치료제 난제도전) (ASM0015) | 2023.0 ~ 2024.12. | In progress |
| 4 | 보건복지부 | 감염병 예방치료 기술개발 (항진균제 내성 진균 감염 치료제) (ATB1651, ATC0001) | 2022.08. ~ 2023.12. | Completed |
| 5 | 보건복지부 | 2022년도 제약산업 전주기 글로벌 진출 강화 지원 사업 | 2022.04. ~ 2022.11. | Completed |
| 6 | 중소벤처기업부 | 창업도약패키지 지원사업 (SAMH) | 2020.05. ~ 2021.03. | Completed |
| 7 | 보건복지부 | 감염병 예방치료 기술개발 (미해결 치료제 도전 기술개발) (ATB1651) | 2020.0 ~ 2021.1 | Completed |
| 8 | 중소벤처기업부 | 중소기업 네트워크형 기술개발 지원사업 | 2018.11. ~ 2020.11. | Completed |
